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August 15, 2025

North Carolina Medicaid: Specialty pharmacy updates

State-required prior authorization requirements

Beginning Dec. 1, 2025, we’ll require notification/prior authorization for the following specialty medications for UnitedHealthcare Community Plan in North Carolina:

Medication HCPCS code(s)
Casgevy® (exagamglogene autotemcel) J3392
Elevidys™ (delandistrogene moxeparvovec-rokl) J1413
Hemgenix™ (etranacogene dezaparvovec-drlb) J1411
Lenmeldy™ (atidarsagene autotemcel) J3391
Luxturna® (voretigene neparvovec-rzyl) J3398
Lyfgenia™ (lovotibeglogene autotemcel) J3394
Roctavian™ (valoctogcogene roxaparvovec-rvox) J1412
Skysona® (elivaldogene autotemcel) J3490, J3590, C9399
Zolgensma® (onasemnogene abeparvovec-xioi) J3399
Zynteglo™ (betibeglogene autotemcel) J3393

How to submit and manage prior authorizations

For training, view our Prior Authorization and Notification interactive guide.

Please note: For the following cell and gene therapies, you must contact Optum Transplant Services at 888-805-1802 to submit your prior authorization request:

  • Casgevy
  • Lenmeldy
  • Lyfgenia
  • Skysona
  • Zynteglo

 

Prior authorization requests must be received before the date of service. If a request is not received in advance, providers are not permitted to balance bill the member if their claim is denied.

Questions? We're here to help.

Connect with us through chat 24/7 in the UnitedHealthcare Provider Portal.

PCA-1-25-01540-M&R-NN_08062025

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